A Comparative Clinical Study On The Effect Of Udvartana And Tummy Trimmer In Udara- Lambanatva W. S. R Central Obesity

Now a day’s Obesity/ Sthoulya is a burning issue, but it is not being easy to burn it. Abdominal obesity also known as central obesity. With all kinds of foods becoming readily available at any times while humans are sedentary, intake of higher energy and less energy expenditure. Ayurveda describes Medopachaya as Sthoulya, it is a Santarpanajanya vyadhi said as one among Asthanindita purusha. According to the WHO, obesity is one of the most common, yet among the most neglected, public health problems in both developed and developing countries. Globally 1 in 6 adults is obese and nearly 2.8 million individuals die each year due to overweight or obesity. India is just behind US and China in this global hazard list of top 10 countries with highest number of obese people. The diuretic and purgatives drugs are also used to treat obesity, but the action is for shorter term and the patients again put on weight after cessation of treatment. In Ayurveda we offer several treatment measures to treat obesity. Here is an attempt made with safety management using principles of Panchakarma. 30 Patients were equally divided in 2 groups and treated Udvartana with Kolakulatthadi churna and Tummy trimmer by Sauna shaping belt, their comparative effects in central obesity. On the other hand corporate sectors are selling commercial slimming belts and are being sold out like hotcakes. Comparing both the procedures, Udvartana has given better result than Tummy trimmer.

Efficacy of Cervical Medial Branch Block in Two Patients with Refractory Occipital Neuralgia.

Occipital neuralgia is often characterized by severe, paroxysmal and debilitating pain in the distribution of greater and lesser occipital nerve. It can cause severe refractory headache. Occipital nerve blocks have been used for long in diagnosis and treatment. We describe the efficacy of cervical medial branch block in patients with refractory occipital neuralgia. Two patients with refractory occipital neuralgia who were earlier treated with medications and occipital nerve block without much benefit were given cervical medial branch block. Visual analogue scale (VAS) score was checked for evaluation of effect of cervical medial branch block. The VAS score at 3 month after cervical medial branch block was significantly decreased compared to baseline scores in both patients. There were no major complications. Our case report suggests that cervical medial branch block can be used as a treatment modality in patients with refractory occipital neuralgia. This also suggests that cervical medial branches are important pain generators located in cervical region, could be an important source of pain in occipital neuralgia.

Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L: potential effectiveness in Alzheimer's and other neurological disorders

BACKGROUND: Atriplex laciniata L. was investigated for phenolic, flavonoid contents, antioxidant, anticholinesterase activities, in an attempt to explore its effectiveness in Alzheimer's and other neurological disorders. Plant crude methanolic extract (Al.MeF), subsequent fractions; n-hexane (Al.HxF), chloroform (Al.CfF), ethyl acetate (Al.EaF), aqueous (Al.WtF), Saponins (Al.SPF) and Flavonoids (Al.FLVF) were investigated for DPPH, ABTS and H2O2 free radical scavenging activities. Further these extracts were subjected to acetylcholinesterase (AChE) & butyrylcholinesterase (BChE) inhibitory activities using Ellman's assay. Phenolic and Flavonoid contents were determined and expressed in mg Gallic acid GAE/g and Rutin RTE/g of samples respectively. RESULTS: In DPPH free radicals scavenging assay, Al.FLVF, Al.SPF and Al.MeF showed highest activity causing 89.41 ± 0.55, 83.37 ± 0.34 and 83.37 ± 0.34% inhibition of free radicals respectively at 1 mg/mL concentration. IC50 for these fractions were 33, 83 and 82 µg/mL respectively. Similarly, plant extracts showed high ABTS scavenging potential, i.e. Al.FLVF (90.34 ± 0.55), Al.CfF (83.42 ± 0.57), Al.MeF (81.49 ± 0.60) with IC50 of 30, 190 and 70 µg/ml respectively. further, H2O2 percent scavenging was highly appraised in Al.FLVF (91.29 ±0.53, IC50 75), Al.SPF (85.35 ±0.61, IC50 70) and Al.EaF (83.48 ± 0.67, IC50 270 µg/mL). All fractions exhibited concentration dependent AChE inhibitory activity as; Al.FLVF, 88.31 ± 0.57 (IC50 70 µg/mL), Al.SPF, 84.36 ± 0.64 (IC50 90 µg/mL), Al.MeF, 78.65 ± 0.70 (IC50 280 µg/mL), Al.EaF, 77.45 ± 0.46 (IC50 270 µg/mL) and Al.WtF 72.44 ± 0.58 (IC50 263 µg/mL) at 1 mg/mL. Likewise the percent BChE inhibitory activity was most obvious in Al.FLVF 85.46 ± 0.62 (IC50 100 µg/mL), Al.CfF 83.49 ± 0.46 (IC50 160 µg/mL), Al.MeF 82.68 ± 0.60 (IC50 220 µg/mL) and Al.SPF 80.37 ± 0.54 (IC50 120 µg/mL). CONCLUSIONS: These results stipulate that A. laciniata is enriched with phenolic and flavonoid contents that possess significant antioxidant and anticholinestrase effects. This provide pharmacological basis for the presence of compounds that may be effective in Alzheimer's and other neurological disorders.

three years prospective study of spinal injuries treated by internal fixation with adjustable titanium cage

Background: the incidence of spinal trauma has risen sharply worldwide in recent years, the main contributors being road side accidents, sports injuries and fall from heights

Objective: the objective of the study is; to assess the postoperative outcome of the intervertebral titanium cage, in patients operated for traumatic unstable thoracolumbar burst fractures

Patients and Methods: this is a prospective study, carried out in the Department of Neurosurgery, Sheikh Zayed Hospital, Rahim Yar Khan, during 3 years, from 1st November, 2005 to 31st October, 2008. All the patients of adult age of either sex, with spinal injury underwent a neurological and radiological assessment, and those patients rendered fit for surgery, were operated upon with an intervertebral adjustable titanium cage. The patients were followed up for one year

Results: the study comprised of 3 7 patients, of all ages with 30 males and 7 females, all were received in the emergency department. The majority of the patients had L 1 fracture 19 [51 %] followed by D 12 fracture in 10 [2 7% ]. The main cause of spinal injury was fall from height in 80% and road side accidents in 20% of cases. The neurological status of the patients received in emergency showed paraplegia in 41 % while Para paresis in 59% of patients. The neurological outcome of 37 patients after one year of follow up showed marked improvement in 22 patients of incomplete spinal cord injury [Para paresis] who showed 100% improvement in their weakness in comparison to little or no improvement in 15 patients of complete spinal cord injury [paraplegia]

Conclusion: our experience with usage of the titanium cage in traumatic vertebra has shown to be very promising, especially in patients of Para paresis and it can become a main stay of surgical management in thoracolumbar burst fractures in our setup